The Emergence of a Superpower Essay Example | Topics and Well Written Essays - 250 words

The Emergence of a Superpower - Essay Example He ended U.S isolationism policy by acting aggressively in foreign matters without even the consent or support of the congress (Oakes 89). Roosevelt also developed a powerful and large navy that was significant to the U.S defense since it served as strong restraint to American foes. Woodrow Wilson as the president of the U.S abandoned the imperialist policy implemented by Theodore Roosevelt and came up with a new means of America dealing with other nations. Despite the fact that he believed that it was the duty of America to change the world, he believed that everybody in the globe had the right to self determination in that they were to decide on the type of government they wanted (Oakes 148). In order to increase U.S influence abroad, Wilson aimed to protect democracy. For instance, Wilson was forced to invade Nicaragua in order to assist the rebels who had ousted a totalitarian regime. Franklin Roosevelt’s foreign policy was overshadowing domestic or local policy because he was more concerned about what was happening in Europe. After refusing to support stabilization of global currency in 1933, he stabilized the dollar in 1934 and started to assist Great Britain and France to stabilize their currencies and keep them from totalitarian nations (Oakes 96). Just like Theodore Roosevelt, Franklin Roosevelt believed that U.S had to develop strong army in order to quarantine aggressive nations such as Germany and Japan. In order, he developed the good neighbor policy, which was a re-examination of the U.S policy in Latin America. During Franklin Roosevelt’s term as president, Latin America was the U.S area of interest, thus, it was significant to make American presence felt in the area (Oakes

Albert Camus the Plague Essay Example for Free

Albert Camus the Plague Essay Can God possibly exist in a world full of madness and injustice? Albert Camus and Samuel Beckett address these questions in The Plague and Waiting for Godot. Though their thinking follows the ideals of existentialism, their conclusions are different. Camus did not believe in God, nor did he agree with the vast majority of the historical beliefs of the Christian religion. His stance on Christianity is summed up most simply by his remark that in its essence, Christianity (and this is its paradoxical greatness) is a doctrine of injustice. It is founded on the sacrifice of the innocent and the acceptance of this sacrifice (Bree 49). Camus felt that Jesus Christ was an innocent man who was unjustly killed. This does conflicts with all of Camus values. However, Camus did not believe that Jesus was the son of God. Camus inability to accept Christian theology is voiced in The Plague by Riex and juxtaposed against the beliefs preached by Father Paneloux (Rhein 42). Panelouxs attitude toward the plague contrasts sharply with Rieuxs. In his first sermon, he preaches that the plague is divine in origin and punitive in its purpose. He attempts to put aside his desires for a rational explanation and simply accepts Gods will. In this way he is not revolting and therefore falls victim to the plague. Father Panelouxs belief that there are no innocent victims is shaken as he watches a young boy die of the plague. Camus purposefully describes a long, painful death to achieve the greatest effect on Paneloux: When the spasms had passed, utterly exhausted, tensing his thin legs and arms, on which, within forty-eight hours, the flesh had wasted to the bone, the child lay flat, in a grotesque parody of crucifixion (215). Paneloux cannot deny that the child was an innocent victim and is forced to rethink his ideas. During his second sermon, a change is seen in Father Paneloux. He now uses the pronoun we instead of you, and he has adopted a new policy in which he tells people to believe all or nothing (224). Father Paneloux, as a Christian, is faced with a decision: either he accepts that God is the ultimate ruler and brings goodness out of the evil that afflicts men, or he sides with Rieux and denies God. The conclusion formed by Camus is that because this is a world in which innocent people are tortured, there is no God. Samuel Beckett does not necessarily deny the existence of God in Waiting for Godot. If God does exist, then He contributes to the chaos by remaining silent. The French philosopher Blaise Pascal noted the arbitrariness of life and that the universe works based on percentages. He advocated using such arbitrariness to ones advantage, including believing in God. If He does not exist, nobody would care in the end, but if He does, a believer is on the safe side all along, so one cannot lose. In this play, either God does not exist, or He does not care. Whichever is the case, chance and arbitrariness determine human life in the absence of a divine power. This ties in with the two tramps chances for salvation. As one critic observes, For just as man cannot live by bread alone, he now realizes that he cannot live by mere thinking or hanging on in vain to a thread of salvation which does not seem to exist (Lumley 203). This explains Vladimir and Estragons contemplation of suicide after Godot remains absent for yet another day. One could also argue, in the absurd sense, that each man has a fifty-fifty chance of salvation. One of the two prisoners who were crucified with Jesus was given salvation. This element of chance for salvation can also be extended to Pozzo and Lucky in Waiting for Godot. When they come across the two tramps, Pozzo is on his way to sell Lucky because he claims that Lucky has grown old and only hinders him. In this way Pozzo is trying to draw that fifty-fifty chance of salvation for himself. One of the ways in which Lucky hinders him is that Lucky could be the one to be redeemed, leaving Pozzo to be damned. Even Luckys speech is concerned with salvation: Given the existence of a personal God outside time without who from the heights of divine apathia divide athambia divide apaia loves us dearly with some exceptions for reasons unknown and suffers with those who for reasons unknown are plunged in torment. (28) After removing all of Luckys nonsensical meanderings, the gist of his speech is that God does not communicate with humans and condemns them for unknown reasons. His silence causes the real hopelessness, and this is what makes Waiting for Godot a tragedy

Odd Couple :: essays papers

Odd Couple Themes and characters are most often the key factors that influence a writer's work. Most of the time the author has no control over this influence. This is clearly shown in Neil Simon's play, The Odd Couple. Not only is Simon's own life depicted in his play, but also the lives of those close to him, can be parallel to his work. Neil Simon's life is depicted in his characters and themes of his play, The Odd Couple. Marvin Neil Simon was born in the Bronx on July 4, 1927. His father, Irving, was a salesman in Manhattan's garment district; his mother Mamie worked in Gimbel's department store. The family moved to Washington Heights, in northern Manhattan, when Simon was young. Irving was an errant husband who occasionally abandoned the family altogether, leaving Mamie, a frustrated and bitter women, alone to deal with Neil and his older brother Danny. Eventually, the parents were divorced, and Neil went to live with relatives in Queens. From an early age, he exhibited a quick wit and an active imagination. He loved films and was often asked to leave the theater for laughing to loud. In high school, Simon was sometimes ostracized as a Jew, an experience that would later inform his work. Meanwhile, he and his brother began collaborating on comedy material that they sold to stand-up comics and radio announcers. Simon graduated from DeWitt Clinton High School in 1944 at the age of sixteen(Magill2216). He entered New York University under the US Army Airforce Reserve Program. Throughout his military career, he wrote for many military newspapers. Discharged in 1946, Simon took a job in the mail room at Warner Brothers in New York, where Danny worked in the publicity department. The brothers were soon hired to write for Goodman Ace of CBS, and over the next decade they provided material for many popular comedians. During the summers of 1952 and 1953, they wrote sketches for a professional acting company at Camp Tamiment, in Pennsylvania. At Camp Tamiment, Simon fell in love with a young actress named Joan Baim, and the couple was married on September 30, 1953. Five years later, Joan gave birth to a daughter, Ellen; a second daughter, Nancy, was born in 1963(Magill2261). In 1956, when Danny Simon moved to California to be a television director, Neil stayed in New York and wrote for many popular television shows. He also adapted broadway plays for television. By the later 1950's, however, he wanted more independence

Great Gatsby and Elizabeth Barret Browning comparison Essay

In what ways do the texts you have studies highlight the changing values of dreams and desires? The concept of dreams and desires are a constantly changing ideal experienced in human nature, and this concept is explored through Elizabeth Barrett Browning’s anthology of poems â€Å"Sonnets of the Portuguese† and Francis Scott Fitzgerald’s satirical novel â€Å"The Great Gatsby.† Correlative thematic concerns arise between the Victorian era and the Jazz Age in relation to dreams and desires and furthermore to the nature of love and perceptions are undertaken making these texts valued upon consideration of each other. Through deconstructing these texts it becomes apparent that these values are influenced by each text’s composer’s contextual influences. Similarly, the role and value of each composer within their context must be undertaken to comprehend the value and perspective of their reconstruction of their era. Elizabeth Barrett Browning’s Victorian context shapes her perception in the evaluation of love and the role of women. In the construction of her poems, ‘Sonnets from the Portuguese’ structured inspiration derives from Romantic prose, whilst pertaining to the strict form. Allowing for a focus on the thematic concerns of her poems rather, Barrett Browning’s poems emphatically explore the progression of the highly idealised love of herself and Robert Browning. Rejecting the social expectations of her context through her presentation to Browning of her deeply personal poems, her poems provide insight to the female perception of courtly love. Through this alone we can see that Barrett Browning is an example herself of changing values as she rejects social conventions of her era by using the sonnet form, which was dominated by males at the time, whilst women tended to be limited to the novel form. She uses this form to present and express to Robert Browning the extent of her love. Love is explored in both texts as a major thematic concern representing changing values of dreams and desires. Jay Gatsby in Fitzgerald’s â€Å"The Great Gatsby† had spent the last 5 years of his life building his dream and perfect fantasy that he wishes to share with Daisy. Throughout the novel his dream and desires are tested yet he still remains hopeful. Out of all the characters Gatsby seems to be the only one with this hope, making him a perfect representation of the changing ideals of love, and furthermore dreams and desires. In Barrett Browning’s time, the notion of love was believed in and practiced through courtship in comparison in the Jazz age  where love was no longer idolised and only one out of so many people has that same kind of hope as nearly 80 years earlier. When comparing these 2 texts we can see that over this time the value of dreams and desires changes, in this case the significance of love becomes less important. In the Great Gatsby, the director uses symbolism to show the changing value of dreams and desires. The green light at the end of Gatsby’s wharf represents his hopes and dreams for the future. It is first brought up in chapter 1 shining brightly; representing his firm belief in his love for daisy, until it gradually loses its strength in Chapter 9 â€Å"Gatsby believed in the green light, the orgastic future that year by year recedes before us.† Throughout the movie his belief in his dreams are tested and through the gradual decrease in the green lights intensity, we can see that it represents Gatsby’s gradual decrease in his belief in his dreams as he realises the problems that arise and how they affect the successfulness of his desires. This change over a short time is also present in Barrett Browning’s sonnets and her love for Robert. In sonnet 1 she describes her love as a shadow drawing her back by the hair, as she doesn’t understand how she’s feeling, she’s unfamiliar with the feelings of love. Gradually by the end of her sonnets she is strong in her love for Robert saying â€Å"how do I love thee, let me count the ways!† as though she loves Robert in more ways than 1 and she knows how she feels now and is certain of those feelings. This represents her own changing values as her dreams and desires are uncertain, yet they become to love Robert and throughout the sonnets we can s ee that she values this love more and more and becomes more confident in that love. When considering the context of Elizabeth Barrett Browning we can recognise the importance of her sonnets and furthermore her love for Robert. When viewed as a whole, her sonnets represent the change she experiences of the value of her love being highlighted. In Fitzgerald’s â€Å"The Great Gatsby† this gradual change idea is also present in the character Jay Gatsby and his loss of value for love and his own dreams and desires. In both these texts we can see that dreams and desires are changing values both in short and longer periods of time. The context of each text is taken into account when deconstructing these texts as it shows the significance of the representation of changing values. Jay Gatsby is the only one in his time who shares the same hope in his dreams and desires as Barrett Browning 80  years prior. Therefore we can see that both the great Gatsby and Sonnets of the Portuguese are texts that highlight changing values of dreams and desires.

Establishing a Claim in Negligence

Introduction In for a claim for negligence to be established the claimant will be required to prove that they have suffered damage and that intentional behaviour or at least recklessness existed. This will allow a determination to be made as to whether the claimants have any possible tort of negligence claims against the defendants. Establishing if the defendant is negligent, the claimant must prove whether there is a duty of care, whether this duty had been breached and the damage was caused by the breach. In Heaven v Pender[1] it was first suggested there should be a general principle of law which governs the duty of care. Lord Atkin in Donoghue v Stevenson[2] provided some guidance in this area by showing that in order to establish a duty of care was owed the so-called ‘neighbour principle’ must be adopted; â€Å"you must take reasonable care to avoid acts or omissions which you can reasonably foresee would be likely to injure your neighbour†. The Court in Dorset Yacht Co L td v Home Office[3] expanded this principle even further when it was made clear what type of circumstances would give rise to a duty of care and was followed by Caparo Industries plc v Dickman[4] which is currently the leading case dealing with the duty of care element. The House of Lords in this case proposed a three-stage test for establishing whether a duty of care has arisen. The courts would need to be satisfied that; a) it would be reasonably foreseeable that the defendant’s failure to take care could cause harm or damage to the claimant; b) that the relationship between the claimant and the defendant was so close that there was an element of proximity between them; and c) that it is fair, just and reasonable to impose a duty of care on the defendant based upon the particular circumstances of the case. Unless this test can be satisfied, a claimant will be unable to establish a claim in negligence since the defendant will not be found to have owed a duty of care to the claimant. Once it has been shown that a duty of care was owed to the claimant, it must then be shown that the duty has been breached. This will be decided by the Court based on a two-stage test; first of all the Court will be required to consider how the defendant should have behaved in such circumstances (question of law) and then decide the extent to which the defendants behaviour fell below this required standard of care (question of fact).[5]Consequently, it must be shown that a reasonable person would have foreseen the danger and subsequently regarded the risk as unreasonable; Blythe v Birmingham Waterworks[6]. As a general rule, a defendant will not be liable unless the risk was foreseeable, was not insignificant and a ‘reasonable person’ would not have taken the necessary precautions in respect of the particular risk that occurred. In making such an assessment the Court will consider what precautions a ‘reasonable person’ would have taken, what the likelihood of harm was and whether a reasonable person could have been expected to bear the costs of avoiding such harm. The test is an objective one; Glasgow Corp v Muir[7] and the issue to be considered is not whether the defendant would have foresaw the risk but whether a reasonable person would have foresaw it based on the particular circumstances of the case. The issue will thus be decided on a case by case basis by reviewing the individual facts of the case. Once it is shown that the defendant owed a duty of care and subsequently breached that duty, causation must then be considered. Essentially, it must be shown that the claimant’s losses were a natural consequence of the breach since the breach caused the harm or damage that occurred. In establishing causation, the ‘but for’ test would need to be applied. This test was established in R v White[8] when it was stated by the Court that the claimant must prove that the harm would not have occurred ‘but for’ the defendants actions. Once this has been established causation will then be proved unless it can also be shown that there is an intervening act which brakes the chain of causation, also known as a novus actus interveniens; Wilsher v Essex Area Health Authority[9] the ‘but for’ test will not established. Remoteness of damage will then be d etermined by considering whether or not the damage was a kind which was foreseeable. Once all of these elements have been proven, the defendant will be found liable for the full extent of the damage; The Wagon mount (no.1)[10]. Jennifer HallamIn June 2013 Jennifer Hallam parked her car opposite the knight’s plaza building where on return to her car she noticed damage to the car. On enquiring from shop owners she was informed that this was due to light reflecting from the building. Jennifer returned the next day and investigated and established this is the case. T Knight Group (TKG) owe a duty of care to Jennifer as the neighbour principle clearly applies to her on the basis that the Jennifer would have been so closely affected by the actions of TKG that they ought reasonably to have had her in their contemplation. TKG would thus have been under a duty to ensure that reasonable care was being taken in order to avoid any harm or damage to third partied caused by their actions. Nevertheless, this could be disputed by TKG as they may be able to demonstrate that the breach of duty did not occur as a result of their own actions. This is because the architects or the structural engineers could instead be held responsible for the design fault. This situation has been seen around the world and also in the UK. Under section 79 of the environmental protection act 1990 the local authority may take action to ensure the nuisance is stopped. There is no reported case in England and Wales in which a Court has been required to determine reflection of sunlight. However in New Zealand this was the case and was seen in Bank of New Zealand v greenwood[11]. This would amount to an actionable tort of nuisance. Here the high Court of New Zealand held that reflected light can constitute an actionable nuisance. In Hunter v Canary Wharf Ltd[12] the Lords considered the New Zealand case and although they said that it was most unusual they did in fact regard the decision as ‘eminently sensible’ and ‘admirable’. In light of this, it could therefore be said that Jennifer’s actions is likely to be successful if the Courts in the UK follow suit. If the Courts do find that there has been a breach, it is likely that they will then be able to establish that the breach caused the harm and was not too remote so as to prevent an action in negligence. This is because, if TKG successful argue that they the architects or the structural engineers are to blame for the damage, then the standard of care will be that based upon their ex pertise; Wilsher v Essex[13]. And, architects and structural engineers will be required to have a reasonable expectation of the risks involved with this type of project and ought to have known of the dangers.RahimRahim Khan has stated that he has suffered a financial loss due to the dazzling sun and high temperatures that are created when the sun reflects off the Knights Plaza Building and onto the pavement outside his shop. There is generally no duty of care owed to individuals to avoid causing others to suffer an economic loss. The economic loss must not relate to personal injury or damage to property as in Spartan Steel & Alloys Ltd v Martin[14]. Nevertheless, in Hedley Byrne & co v Heller[15] the House of Lords held that economic loss could be caused by negligence misstatement rather than a negligent act, although it is unlikely to apply here. In Linklaters Business Services v Sir Robert McAlpine[16], however, it was noted by the Court that; â€Å"It may well be arguable in the case of complex structures that one element of the structure should be regarded for the purpose of the application and the principles [regarding economic loss] as distinct from another element, so that damage to one part of the structure caused by a hidden defect in another part may qualify to be treated as damage to other property.† It will depend entirely upon the facts of the case as to whether a claim by Rahim will prove to be a success although it is questionable whether this will be established given the complexity of establishing pure economic loss. Thus, Rahim will have to demonstrate that the relationship between Rahim and TKG was sufficiently close for a claim to be ascertained for economic loss. This is unlikely to be established given that Rahim merely owns a nearby sandwich shop and so the requirements are unlikely to be satisfied here. In addition, Rahim also stated that his business has just reopened after health inspector closed it down after allegations of food poisoning. This could be significant as the loss could have been caused by the closure of the shop for 6 months. The chain of causation (novus actus interveniens) could have been broken by the fact the shop was closed. In certain cases, the chain of causation is capable of being broken by an intervening act. Therefore, the defendant may not be liable if the chain is broken by the intervening act even if there exists a duty of care as in Kirkham v Chief[17]. Thus, as put by Finch and Fafinski â€Å"if the novus actus interveniens is sufficient to break the chain , then the defendant may not be liable despite being in breach of the duty of care.†[18] Accordingly, it is therefore unlikely that TKG will be found liable in tort for the loss that was suffered by Rahim since it is likely that the loss would have occurred regardless; The Oropesa[19]. Rahim is also being prosecuted having been caught on CCTV cameras throwing stones and subsequently causing damage to the Knights Plaza Building costing ?75,000. In common law Rahim would be found criminally liable for criminal damage under section 1 (1) of the Criminal Damage Act 1971 for destroying property that belonged to another with the intention or recklessness as to whether damage was caused. The fact that Rahim was caught on CCTV throwing stones at the building is sufficient enough to find him liable under this section. Accordingly, it is clear that Rahim had the intention to damage the property by throwing the stones as he was angry at TKG for the loss of profits in which he claims to have suffered. In addition, for criminal damage to be established, it does not have to be shown that the property is no longer usable. The fact that some damage was caused will be sufficient as in Roper v Knott[20]. Accordingly, Rahim will thus be found criminally liable for damaging the proper ty and causing ?75,000 worth of damage. Andy Pandy, Mandy Pandy and Muz Ahmed In deciding whether Darren is liable for the death of Andy Pandy and the injuries sustained by Mandy Pandy and Muz Ahmed, it will need to be considered whether Darran owed them a duty of care. Applying the Caparo test, it is evident that a duty of care was owed to Andy, Mandy and Muz. This is because all three of them can be considered to have a relationship of proximity to Darran that he ought to have had them in his contemplation. Hence, drivers owe a duty of care to pedestrians so it is evident that this part of the test will have been satisfied. Nevertheless, it is questionable whether Darran failed to take care given that the gust of wind is likely to have been unforeseeable and as such it would not be fair, just and reasonable to impose duty of care on him. In addition, although Darran caused the accident to occur it can be said that there was an intervening act that broke the chain of causation. This is because the accident would not have happened had it not been for the struc ture of the building and because these defects were known to the TKG since May 2013, they could have alleviated these problems by taking the necessary steps. In view of this, the TKG should be found liable for the death of Andy since they ought to have taken reasonable precautions to prevent the problem from occurring. Essentially, because they had not taken any steps to prevent the problem from occurring it is clear that they should be found liable as they would have owed Andy a duty of care, they were in breach of that duty and the breached caused the harm. The same will apply in relation to Mandy and Muz since it would not be fair, just and reasonable to impose liability on Darran for the psychiatric harm that was caused and so TKG ought to be held liable for this also. In order to establish a claim in negligence for psychiatric injury, all of the negligence requirements must first be satisfied. However, further difficulties will arise since Mandy and Muz will not be awarded compensation unless three additional requirements are satisfied; a) there was a close tie of love and affection between the parties; b) that the victim was close to the accident at the time, and c) that the accident was directly perceived.[21] It is likely that Mandy will be able to establish all three given that Andy was her brother, although it will be more difficult for Muz to demonstrate that there was a close tie of love and affection. In addition, it will also have to be shown that the harm or damage caused was reasonably foreseeable, which again will be like ly to prove complex; Alcock v Chief Constable of Yorkshire[22]. In Page v Smith[23], nonetheless, the defendant was found liable even though the claimant was not physically hurt the car crash that was caused by the defendant. Therefore, it is possible that both Mandy and Muz will be able to establish a claim against TKG as shown in Dulieu v White[24]. If it is shown that the harm is too remote, however, they will not be able to establish a claim. Conclusion Overall, it is likely that TKG will be found liable for the damage that has been caused to Jennifer’s car, the death of Andy and the psychiatric injury caused to Mandy and Muz, unless they can demonstrate that the architects and structural engineers are to blame. It is unlikely that Rahim’s claim will succeed and instead he will be found criminally liable for the damage caused to the building. Damages fall into two categories, pecuniary and non-pecuniary losses. Pecuniary losses are calculated into monetary terms whereas non-pecuniary losses are not. However, whether or not damages will be awarded will be dependent upon the remoteness of the harm or damage that was caused Bibliography Finch, E. and Fafinski, S. (2010) Law Express: Tort Law, 3rd Edition, Longman. Kidner, R. (2010) Casebook on Torts, 11th Edition. The Law Commission., ‘Liability for Psychiatric Illness’ (1998) Law Com No 249, 2. Cases Alcock v Chief Constable of Yorkshire [1992] 1 AC 310 Bank of New Zealand v greenwood [1984] 1 NZLR 525 Blythe v Birmingham Waterworks (1856) 11 Exch 781 Caparo Industries plc v Dickman [1990 1 All ER 568 Donoghue v Stevenson [1932] AC 562 Dorset Yacht Co Ltd v Home Office [1970] AC 1004 Glasgow Corp v Muir [1943] AC 448 Hedley Byrne & co v Heller [1963] 3 WLR 101 Heaven v Pender (1883) 11 QBD 503 Hunter v Canary Wharf Ltd [1997] 2 WLR 684 Kirkham v Chief [1990] 2 KB 283 Linklaters Business Services v Sir Robert McAlpine [2010] EWHC 1145 (TCC) Page v Smith [1996] AC 155 Roper v Knott [1898] 1 QB 868 R v White (1910) 2 KB 124 Spartan Steel & Alloys Ltd v Martin [1972] 3 WLR 502 The Oropesa [1943] 1 All ER 211 Wilsher v Essex Area Health Authority [1988] AC 1074

How to Use a Dash

How to Use a Dash The dash (- )  is a mark of punctuation  used to set off a word or phrase after an independent clause or a parenthetical remark (words, phrases, or clauses that interrupt a sentence). Dont confuse the dash (- ) with the hyphen (-): the dash is longer. As William Strunk Jr. and E.B. White explained in The Elements of Style: A  dash  is a mark of separation stronger than a  Ã¢â‚¬â€¹comma, less formal than a  colon, and more relaxed than  Ã¢â‚¬â€¹parentheses. There are actually two types of dashes, each with different uses: the  em dash- also called the long dash, according to Oxford Online Dictionaries- and the  en dash, which doesnt have another name but falls between the hyphen and em dash in terms of length.  The  en dash  is so named because it is approximately the equivalent width of the uppercase letter  N  and the  em dash  is roughly the width of an uppercase  M. Origins Merriam-Webster says the word  dash  comes from the  Middle English word  dasshen, which probably derives from the Middle French term  dachier,  meaning to impel forward. One current definition of the word  dash  is to break, which would well describe what a dash does in syntax. The  Online Etymology Dictionary  says the dash- a horizontal line used as a punctuation mark- first appeared in writing and printing in the 1550s. By the late 1800s, the dash had taken on some very specific roles. According to  Thomas MacKellar, in his 1885 book, The American Printer: A Manual of Typography : The em dash...is frequently used in particular works as a substitute for the comma or for the colon, and is found particularly serviceable in rhapsodical writing, where interrupted sentences frequently occur.   MacKellar noted several specific uses for the dash, including: A sign of repetition in catalogs of goods, where it means  ditto.In catalogs of books, where it was used instead of repeating an authors name.As a stand-in for the words  to  and  till, as in chap. xvi. 13-17. The last use would today be an  en dash, which indicates a range. The En Dash Though the Associated Press does not use the  en dash, the press service nicely describes how other styles  do  use the shorter dash.  Some other styles call for  en dashes  to indicate ranges of dates, times, or page numbers, or with some compound modifiers. For example: He worked from 9–5.  She works from 8 a.m.–5 p.m.The festival will take place March 15–31.For your homework, read pages 49–64. To create an  en dash  using a keyboard on a Windows-based system, hold down the Alt key and simultaneously type 0150. To create this punctuation mark on a  Macintosh-based system  hold down the Option  key  and press the Minus key  [-].  American Psychological Association notes that you would use the  en dash  for: Items of equal weight (test–retest, male–female, the Chicago–London flight).Page ranges (in references, â€Å"...Journal of Applied Psychology,  86, 718–729†).Other types of ranges (16–30 kHz). Angela Gibson, writing for the MLA Style Center, a writing resource for the Modern Languages Association, says the organization uses an en dash when a single compound adjective is a proper noun, as in: Pre–Industrial Revolution city. She notes that the MLA also calls for an  en dash when a compound in the predicate position includes a proper noun: The crowd was Beyoncà © Knowles–obsessed. The Em Dash The AP, which does use  em dashes, explains that these punctuation marks are  used: To signal an abrupt change.To set off a series within a phrase.Before attribution to an author or composer in some formats.After datelines.To start lists. AP style calls for a space on both sides of an  em  dash, but most other styles, including MLA and APA, omit the spaces. On a Windows-based system, you can form an  em dash  on a keyboard by holding down the Alt key and typing  Ã¢â‚¬â€¹0151. To create the em dash on a Macintosh-based system, hold down the  Shift  and  Option  keys and press the  Minus  key [-], notes  Techwalla, adding that alternatively, you can press the  Hyphen  key twice and press  Space. There are two basic ways to use an  em dash  in a sentence: After an independent clause: Author Saul Below, in My Paris, provides an example of using an  em dash  after an independent clause: Life, said Samuel Butler, is like giving a concert on the violin while learning to play the instrument- that, friends, is real wisdom. To set off words and phrases:  Writers have effectively used  em dashes  to shoehorn a parenthetical thought or remark into a sentence, as this quote illustrates: Copper Lincoln cents- pale zinc-coated steel for a year in the war- figure in my earliest impressions of money.- John Updike, A Sense of Change,  The New Yorker, April 26, 1999 Thoughts on the Dash For a tiny punctuation mark, the dash has sparked an unusual level of debate among writers, grammarians, and punctuation experts. The dash is seductive, says Ernest Gowers in The Complete Plain Words, a style, grammar, and punctuation reference guide. It tempts the writer to use it as a punctuation-maid-of-all-work that saves him the trouble of choosing the right stop. Some have expressed support for the dash: The dash is less formal than the semicolon, which makes it more attractive; it enhances conversational tone; and...it is capable of quite subtle effects. The main reason people use it, however, is that they know you cant use it wrongly.- Lynne Truss, Eats, Shoots Leaves Other writers strenuously oppose using the mark: The problem with the  dash- as you may have noticed!- is that it discourages truly efficient writing. It also- and this might be its worst sin- disrupts the flow of a sentence. Dont you find it annoying- and you can tell me if you do, I wont be hurt- when a writer inserts a thought into the midst of another one thats not yet complete?- Norene Malone, The Case- Please Hear Me Out- Against the Em Dash.  Slate, May 24, 2011 So, next time you look in your toolkit of punctuation marks and see the  en dash  or  em dash  just waiting to be put to work, ensure that you are using these marks for the right reasons and following the rules discussed. Ask yourself if your  parenthetical remark  will add nuance and insight to your writing or just confuse the reader. If its the latter, return the dashes to your punctuation tool bag and use a comma, colon, or semicolon instead, or revise the sentence so that you can omit the dreaded dash. Source Gowers, Ernest. Plain Words: A Guide to the Use of English. Rebecca Gowers, Paperback, Penguin UK, October 1, 2015.

The Role of O-acetylserine Sulfhydrylase in Cysteine Biosynt essays

The Role of O-acetylserine Sulfhydrylase in Cysteine Biosynt essays The Role of O-acetylserine Sulfhydrylase in Cysteine Biosynthesis in Salmonella tryphimurium: A structural and functional Analysis Pyridoxial 5-phosphate (PLP) acts as a cofactor in many enzymes involved in diverse aspects of amino acid metabolism such as transamination, /-elimination, /-replacement and racemization. In all PLP-dependant enzymes the carbonyl group of the PLP coenzyme binds to an -amino group of a lysine residue in the active site, forming an internal aldimine. O-Acetylserine sulfahydrylase (OASS), isolated from Salmonella typhimurium, belongs to the -family of PLP-dependant enzymes and catalyzes the last step in the cysteine biosynthesis pathway via -replacement, converting O-acetylserine (OAS) to cysteine, upon exchanging acetate in the OAS side chain for sulfide (Fig. 1). The structural and functional framework underlying the reaction mechanism for OASS has been characterized extensively by kinetic studies, site-directed mutagenesis, UV-visible fluorescence and phosphorescence spectroscopy and x-ray structural determination. Three conformationally distinct open, closed, and inhibited s tates were elucidated. Overall Topology and Protein Folding The structures of all proteins can be described in a hierarchical manner relating four levels of organization. The primary level is the amino acid sequence. The secondary level is constructed by motifs in backbone conformations, stabilized by hydrogen bonding, such as helices and -sheets. Tertiary structure describes the complete folded three-dimensional shape of a single chain, and quaternary structure is the association of folded chains to make oligomeric proteins. The nature of the final folded protein, including quaternary structure, is the net result of both enthalpic (H) and entropic (S) optimization to achieve the lowest or most negative free energy (...